Pyridine-3-boronic acid, CAS 1692-25-7, is a heteroaryl boronic acid used as a building block in organic synthesis. Its pyridine ring and boronic acid group make it a reagent for forming carbon–carbon bonds, including in Suzuki–Miyaura cross-coupling chemistry. The compound has the molecular formula C5H6BNO2 and a calculated molecular weight of 122.92 g/mol. For procurement, buyers should confirm the required grade, assay, packaging, and batch-specific documentation with the supplier rather than assume specifications are universal.
This guide is intended for procurement teams, process chemists, research and development laboratories, and manufacturers sourcing Pyridine-3-boronic acid. It outlines the compound’s identity, common synthetic role, specification points, and practical supplier questions. It is not a substitute for a product-specific certificate of analysis, safety data sheet, or process validation. Buyers should use the documents supplied for the actual batch when making technical and handling decisions.
Pyridine-3-boronic acid is also referred to as pyridin-3-ylboronic acid or 3-pyridineboronic acid. The “3” indicates that the boronic acid substituent is attached at the 3-position of the pyridine ring. That position matters because changing the substitution pattern can change a compound’s reactivity and the properties of the final product.
The molecule combines a heteroaromatic pyridine ring with a boronic acid functional group. In a coupling reaction, the boron-containing group can participate in bond formation with a suitable coupling partner under compatible conditions. Actual reaction performance depends on the substrate, catalyst, base, solvent, temperature, and other process variables; the CAS number alone cannot predict yield or selectivity.
| Item | Information | Procurement note |
|---|---|---|
| Product name | Pyridine-3-boronic acid | Confirm the positional isomer on the quotation and label. |
| CAS number | 1692-25-7 | Use with the chemical name to verify identity. |
| Molecular formula | C5H6BNO2 | Confirm that the offered product matches the required form. |
| Molecular weight | 122.92 g/mol | Useful for stoichiometric calculations; verify for any specified form. |
The product is commonly handled as a solid, but appearance and physical condition should be checked against the supplier’s current specification and batch documentation. Do not infer water content, solubility, or stability from the name alone. If a particular physical form or analytical limit is essential, state it explicitly in the inquiry and request confirmation before ordering.
A common role for Pyridine-3-boronic acid is as a coupling partner for introducing a pyridin-3-yl unit into another molecule. This can support the preparation of substituted heteroaromatic compounds for research, medicinal chemistry, and other chemical development work. Whether it suits a specific route depends on the other reactant and the reaction system, so buyers should assess it against the intended chemistry rather than treating all boronic acids as interchangeable.
For early-stage work, researchers may use the compound to explore structural analogues or establish a synthetic route. For scale-up, the decision also involves repeatability, impurity control, material handling, and continuity of supply. A successful small-scale reaction does not by itself establish process performance at a larger scale; validation should be conducted under the intended operating conditions.
First confirm that the required substituent is at the 3-position, not the 2- or 4-position. Next, determine whether the project calls for the free boronic acid or a different boron-containing reagent; these materials may have different handling and reaction characteristics. If the synthesis specifies a particular form, purity threshold, or analytical method, include that requirement in the request for quotation.
Buyers should also consider the stage of the project. A laboratory evaluation may prioritize identity confirmation and a suitable small pack size, while process development may require tighter impurity controls, defined packaging, or repeat-lot availability. These are purchasing considerations to confirm with the supplier, not universal properties of the chemical.
Request a current specification and a batch-specific certificate of analysis where available. Review the stated assay, identification tests, appearance, and any limits relevant to your process, such as water or residual solvents. Analytical methods and acceptance criteria can differ between suppliers, so compare the actual documents rather than relying on a single headline purity figure.
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Ask what documentation is available for the specific shipment, including the safety data sheet and shipping or handling information. Confirm whether the certificate reports measured results or only release limits, and check that the product name, CAS number, lot number, and packaging details are consistent across documents. If your organization requires a specific analytical method or document format, explain that before placing the order.
Packaging should be suitable for the order size, transport route, and your site’s receiving procedures. Discuss container type, closure, labeling, and any requested protective measures with the supplier, then follow the product-specific safety data sheet and internal procedures. Do not assume a storage temperature or shelf life unless it is stated in the supplier’s documentation for the offered material.
For sensitive processes, ask whether the supplier can provide handling guidance or clarify recommended storage conditions based on its product information. Once received, inspect the container and label, record the lot number, and store the material according to the supplied documentation. These steps help preserve traceability between procurement, laboratory use, and any subsequent scale-up assessment.
Price and lead time are dependent on requested quantity, current stock, packaging, destination, and other order conditions. Minimum order quantity can also vary by supplier and pack configuration. Because these details are not fixed chemical properties, buyers should request a current quotation rather than rely on an old price or assume a standard lead time.
For a comparison between suppliers, use the same written requirement for each inquiry. Specify the CAS number, required quantity, target assay or other critical limits, documentation needs, destination, and preferred delivery schedule. This makes differences in quotation scope easier to identify and reduces the risk of comparing products offered under different assumptions.
A capable supplier should be able to clarify product identity, available grades, current packaging options, documentation, and commercial terms for the requested batch. Buyers can also ask how changes in quantity or specification may affect availability and quotation. Clear answers help procurement and technical teams assess fit without treating unconfirmed capabilities as guaranteed.
Maison Chemical supplies Pyridine-3-boronic acid CAS 1692-25-7 for B2B inquiries. We can discuss your target quantity, required specification, packaging preference, and documentation needs so that the offer can be evaluated against your project. Availability, lead time, and order conditions should be confirmed directly for each inquiry.
Pyridine-3-boronic acid CAS 1692-25-7 is a heteroaryl boronic acid used as a building block in organic synthesis, particularly where a pyridin-3-yl group is required. Its key identity data include the formula C5H6BNO2 and molecular weight 122.92 g/mol, while performance in a reaction depends on the specific chemistry and process conditions. Supplier specifications, analytical results, and handling guidance should be confirmed for the actual batch.
As a next step, prepare an inquiry that states the required quantity, target grade or assay, documentation expectations, packaging needs, and delivery destination. Maison Chemical can review those requirements and provide current supply information for evaluation. Confirm the quotation and batch documents before purchase so the material aligns with your technical and procurement criteria.
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