4-Chlorophenylboronic acid CAS 1679-18-1: Uses, Specifications, and Sourcing Guide

13, Oct. 2026

 

4-Chlorophenylboronic Acid CAS 1679-18-1: Uses, Specifications, and Sourcing Guide

4-Chlorophenylboronic acid (CAS 1679-18-1) is an organoboron building block used mainly to introduce a 4-chlorophenyl group into molecules through carbon–carbon bond-forming reactions, especially Suzuki–Miyaura coupling. Buyers should assess more than the product name: confirm identity, assay basis, impurity controls, packaging, documentation, and batch availability against the needs of the intended process. Its molecular formula is C6H6BClO2, and its molecular weight is 156.37 g/mol. At Maison Chemical, we recommend confirming the required grade and documentation before requesting a firm quotation.

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Who This Guide Is For

This guide is intended for procurement teams, process chemists, R&D groups, and manufacturers evaluating 4-Chlorophenylboronic acid for laboratory development or production use. It can help buyers frame a request for quotation and compare supplier responses on relevant technical and commercial details. It is not a substitute for reviewing a product-specific specification, safety data sheet, or process validation. Requirements can differ considerably between a screening experiment and a controlled manufacturing process.

What the Compound Is and How It Is Used

Basic chemical context

4-Chlorophenylboronic acid is an arylboronic acid: a phenyl ring bearing a chlorine substituent at the para position and a boronic acid group. The boronic acid functionality makes the compound useful as a coupling partner in appropriate catalytic reactions. The chlorine substituent remains available for further chemical transformation in some synthetic routes, although its behavior depends on the reaction design and conditions. Buyers should specify the exact positional isomer, since similarly named chlorophenylboronic acids are not interchangeable by identity.

Typical application matching

A common use is Suzuki–Miyaura coupling with a suitable organic halide or related electrophile to form a biaryl or other carbon–carbon bond. The resulting products may serve as intermediates in pharmaceutical, agrochemical, and fine-chemical research or manufacturing. Whether this particular building block is suitable depends on the target structure, reaction compatibility, and the performance established in the buyer’s own process. We recommend evaluating it against the reaction’s required selectivity and impurity profile rather than assuming that a generic application description guarantees a specific result.

  • Route development: Evaluate the compound as a coupling partner during synthesis planning and reaction screening.
  • Intermediate manufacture: Confirm that assay, impurity limits, and batch consistency meet process requirements.
  • Further functionalization: Consider whether the para-chloro substituent is intended to remain in the product or participate in a later step.

Specifications and Material Options

Commercial availability and specification details can vary by supplier, grade, and batch. A product title alone does not establish an assay, residual-solvent profile, water content, or particle-size distribution. Request a current product specification and batch-specific Certificate of Analysis (CoA), and confirm which tests are actually reported. The molecular weight of 156.37 g/mol is a useful identity cross-check, but it does not replace analytical confirmation.

Item to confirm Buyer’s review point
Identity Confirm CAS 1679-18-1, chemical name, positional isomer, and formula C6H6BClO2.
Assay State the minimum acceptable assay and ask whether the result is reported on an as-is or dry basis. For example, 98% can be used as a buyer’s requested threshold, not as a universal or guaranteed product value.
Impurities Identify process-relevant impurities and request limits or test results where they are important to your application.
Physical and analytical data Request the supplier’s reported appearance and available identification or assay methods; do not infer these from the product name.
Documentation Confirm the availability and revision date of the CoA, safety data sheet, and any additional documents required for your organization.

How to Select a Suitable Grade

1. Define the intended use

Begin by stating whether the material is for exploratory research, route scale-up, or routine manufacturing. This helps establish which specifications are essential and which are preferences. If a downstream step is sensitive to a particular impurity, describe that concern when requesting a quotation. A general high-assay requirement may not address a specific process risk.

2. Compare specifications on the same basis

Review assay methods and reporting bases before comparing percentages between offers. An assay stated on a dry basis may not be directly comparable with an as-is result, and different analytical methods can produce results that require context. Ask suppliers to identify the method used and the tests included on the CoA. If your internal acceptance method differs, discuss the difference before placing an order.

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3. Confirm sample and order quantities

For an initial evaluation, buyers may request a small sample, such as 10–50 g, if the supplier can support that quantity. For commercial pricing, provide a realistic forecast and ask for quotations at relevant order breaks—for example, 1 kg, 5 kg, and 25 kg where those quantities fit the project. These figures are request-planning examples, not a statement of Maison Chemical’s standard pack sizes or minimum order quantity. Confirm the actual available pack, MOQ, and whether sample and production material can be supplied on compatible specifications.

4. Assess supply and documentation needs

Ask about current stock or production status, expected dispatch timing, packaging, and shipment terms. Lead time can depend on availability, order size, destination, and documentation requirements, so request a written estimate for the specific order. For a regulated or quality-controlled project, identify document and change-notification expectations early. A supplier should clarify what it can provide rather than implying that every requested document is automatically included.

Pricing, MOQ, and Lead-Time Considerations

The price of 4-Chlorophenylboronic acid can depend on order quantity, specification, packaging, availability, and delivery destination. A quote should identify the quoted grade and quantity, currency, validity period, shipping basis, and any applicable charges. MOQ and sample policies are supplier-specific, so buyers should confirm them directly instead of relying on generic market assumptions. For a fair comparison, evaluate the full offer—including documentation and delivery terms—alongside the unit price.

When planning a project, distinguish quoted lead time from transit time and allow time for incoming inspection. If a delivery date is critical, ask the supplier to confirm the schedule for the requested quantity and shipping route. Do not treat an indicative estimate as a guaranteed delivery date unless the supplier explicitly confirms that commitment. Share forecast changes early when possible, particularly when repeat supply is important.

Supplier Evaluation Checklist

Use the following checklist to organize supplier discussions and reduce avoidable gaps between a quotation and the material your process requires. Focus on verifiable information tied to the offered product and batch. If a point is not relevant to your use, record that decision rather than leaving the requirement ambiguous. Clear written specifications make supplier comparisons and incoming review more consistent.

  • Does the quotation identify 4-Chlorophenylboronic acid and CAS 1679-18-1?
  • Are the assay threshold, reporting basis, and relevant impurity requirements stated?
  • Can the supplier provide a batch-specific CoA and current safety data sheet?
  • Are sample availability, MOQ, packaging, and order quantities confirmed?
  • Are lead time, shipping terms, and quotation validity clear?
  • Can the supplier explain its process for handling specification or document questions?

Key Takeaways and Next Steps

4-Chlorophenylboronic acid CAS 1679-18-1 is a para-chloro arylboronic acid commonly considered for Suzuki–Miyaura coupling and related synthetic planning. A sound sourcing decision depends on matching identity, assay basis, impurity controls, documentation, quantity, and delivery expectations to the intended application. The molecular weight is 156.37 g/mol, while commercial assay and supply terms should be confirmed for the specific offered grade and batch. Buyers should use illustrative targets, such as a requested 98% minimum assay, only as requirements to discuss—not as assumptions about an unverified product.

To request a quotation from Maison Chemical, provide the required quantity, target assay, any critical impurity limits, intended use, destination, and required documents. We can review those requirements and clarify the applicable product specification, sample options, MOQ, packaging, and estimated lead time before an order is placed. This gives your team a practical basis for deciding whether the offered material fits your technical and procurement needs.

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