What Is 3,5-Difluorophenol CAS 2713-34-0? Properties, Uses, and Supplier Information

22, Sep. 2026

 

What Is 3,5-Difluorophenol CAS 2713-34-0? Properties, Uses, and Supplier Information

3,5-Difluorophenol, identified by CAS 2713-34-0, is a fluorinated aromatic phenol used primarily as a building block in pharmaceutical, agrochemical, and specialty organic synthesis. Its molecular formula is C6H4F2O, and its commonly listed molecular weight is 130.09 g/mol. At Maison Chemical, we supply this intermediate for buyers who need reliable identity confirmation, specification alignment, packaging coordination, and export support. Because commercial specifications and handling requirements can vary by batch and application, we recommend confirming the current specification and SDS before purchase.

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Direct Definition and Chemical Identity

3,5-Difluorophenol is a phenolic compound containing a hydroxyl group and two fluorine substituents on a benzene ring. The fluorine atoms are positioned at the 3- and 5-positions relative to the hydroxyl group, giving the molecule a defined substitution pattern that can be useful in route design. The CAS number 2713-34-0 is the primary identifier buyers should use when requesting quotations, technical documents, or sample materials.

The compound belongs to the fluorinated aromatic intermediate family. Its phenolic hydroxyl group can participate in further chemical transformations, while the fluorine substituents influence the electronic character and reactivity of the aromatic ring. These features make 3,5-Difluorophenol suitable for use as a starting material or intermediate rather than as a general-purpose solvent or finished formulation ingredient.

Item Information
Product name 3,5-Difluorophenol
CAS number 2713-34-0
Molecular formula C6H4F2O
Common molecular weight 130.09 g/mol
Chemical class Fluorinated aromatic phenol

Core Functions and Chemical Value

The main value of 3,5-Difluorophenol is its role as a structurally defined intermediate. In synthetic chemistry, the phenolic group may be converted or incorporated into more complex molecules, depending on the selected reaction pathway. The aromatic fluorine atoms can remain in the final structure or influence subsequent substitution and coupling strategies.

From a buyer’s perspective, the compound offers a compact and clearly identifiable starting point for laboratory development, process research, and custom synthesis. However, the exact reaction suitability depends on the reaction conditions, catalyst system, protecting-group strategy, and downstream product requirements. I therefore recommend evaluating the material against the complete synthetic route rather than selecting it solely because it contains a phenol group or fluorine atoms.

Typical Application Scenarios

Pharmaceutical and Medicinal Chemistry Research

3,5-Difluorophenol may be used in the preparation of fluorinated aromatic compounds investigated during pharmaceutical research. Medicinal chemistry teams often use substituted phenols as intermediates for analogue preparation and structure-activity relationship studies. The compound itself should not be described as an active pharmaceutical ingredient unless it has been specifically developed, tested, and registered for that purpose.

Agrochemical and Specialty Synthesis

Fluorinated aromatic building blocks are also used in research related to agrochemical and specialty chemical structures. 3,5-Difluorophenol can serve as one input in a multistep route where controlled substitution and functional-group conversion are required. The suitability of this material depends on the target structure, the intended scale, and the customer’s internal process validation.

Custom Organic Synthesis and Process Development

Contract research organizations, university laboratories, and process development groups may purchase this product for route screening or intermediate preparation. Small quantities can support reaction feasibility work, while larger quantities may be considered after analytical and process requirements are confirmed. For scale-up, buyers should review impurity limits, batch consistency, packaging, transport classification, and expected replenishment time before committing to a production schedule.

Material Options and Specification Considerations

Buyers may encounter different commercial presentations of 3,5-Difluorophenol, including research-scale material, development-grade material, and larger-volume supply. These descriptions should not be treated as universal regulatory grades because the meaning of “technical,” “industrial,” or “high purity” can differ between suppliers. I advise buyers to request the exact specification sheet rather than relying on a grade name alone.

Important specification items may include assay, water content, residue on ignition, color or appearance, related substances, and analytical identification. Depending on the application, customers may also request chromatographic data, lot-specific certificates of analysis, or additional tests. Maison Chemical can discuss the required documentation and help determine which controls are relevant to the intended synthesis.

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Key Properties and Handling Considerations

3,5-Difluorophenol is an aromatic phenol and should be handled as a laboratory or industrial chemical, not as a consumer product. Phenolic compounds may cause irritation or harm through contact, inhalation, or ingestion, but the precise hazard classification must be taken from the current supplier SDS and applicable local regulations. Appropriate controls generally include trained personnel, suitable gloves, eye protection, protective clothing, and effective ventilation.

Storage should follow the product SDS and the customer’s chemical management procedures. Buyers should protect the material from unsuitable heat, incompatible chemicals, and conditions that could compromise container integrity or product quality. A practical purchasing specification should also state the expected container size, storage environment, retest or shelf-life information where applicable, and the required shipping documentation.

  • Identity: Confirm the product name and CAS 2713-34-0.
  • Composition: Review the stated assay and impurity profile.
  • Documentation: Request an SDS and a lot-specific certificate of analysis when required.
  • Packaging: Match the package size to laboratory, pilot, or production requirements.
  • Safety: Use the current SDS for handling, storage, and transport decisions.

How Buyers Should Select a Supplier

The lowest quoted price is not always the lowest total procurement cost. A more reliable comparison considers the specification, document quality, packaging, minimum order quantity, lead time, shipping method, and ability to support repeat orders. For a multistep synthesis, delays or inconsistent material quality can create costs that exceed the initial price difference.

Questions to Ask Before Ordering

  1. Can the supplier confirm the product identity as 3,5-Difluorophenol, CAS 2713-34-0?
  2. What assay and impurity limits apply to the offered batch?
  3. Is a current SDS available for the destination market?
  4. Can the supplier provide a certificate of analysis for the shipped lot?
  5. What are the available package sizes, minimum order quantity, and estimated lead time?
  6. Can the supplier support samples, repeat purchases, or customized documentation?

I also recommend checking whether the quoted material is available from current stock or depends on a new production campaign. Stock availability, export controls, hazardous-goods requirements, and destination-country import procedures can all affect delivery timing. These questions are particularly important when 3,5-Difluorophenol is a critical starting material in a scheduled development program.

Maison Chemical Supplier Support

Maison Chemical supports B2B buyers seeking 3,5-Difluorophenol CAS 2713-34-0 for pharmaceutical intermediates, specialty synthesis, and research applications. We focus on confirming the requested identity and specification before quotation, so customers can compare the offer against their actual process requirements. Our team can discuss packaging, documentation, sample needs, order quantity, and destination information during the inquiry stage.

For repeat or scale-sensitive projects, I encourage customers to share the expected annual or project volume, target purity, preferred packaging, delivery destination, and required documents. This information helps us assess the most appropriate supply arrangement without making unsupported assumptions about the customer’s route or regulatory obligations. Final availability, pricing, lead time, and shipping conditions should be confirmed in a product-specific quotation.

Summary Insight

3,5-Difluorophenol CAS 2713-34-0 is a fluorinated aromatic phenol with the molecular formula C6H4F2O and a commonly listed molecular weight of 130.09 g/mol. Its principal role is as a synthetic intermediate for pharmaceutical research, agrochemical development, specialty chemistry, and custom organic synthesis. The most important purchasing considerations are verified identity, assay and impurity requirements, SDS availability, packaging, lead time, and supplier communication.

Conclusion and Next Steps

In direct answer to the question, 3,5-Difluorophenol is a defined fluorinated phenolic building block used mainly to prepare more complex organic molecules. It can be a practical choice when a synthesis requires the specific 3,5-difluorophenyl structure, but the correct grade and specification must be matched to the customer’s process. Buyers should review technical documents and safety information before placing an order.

To begin a B2B inquiry with Maison Chemical, provide the required quantity, target specification or purity, packaging preference, destination country, and desired delivery schedule. We can then evaluate the appropriate supply option and provide product documentation for review. Contact Maison Chemical for a quotation and technical discussion regarding 3,5-Difluorophenol CAS 2713-34-0.

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