4-Methoxyphenylboronic acid CAS 5720-07-0: A Sourcing and Specification Guide

29, Sep. 2026

 

4-Methoxyphenylboronic Acid CAS 5720-07-0: A Sourcing and Specification Guide

If you are sourcing 4-Methoxyphenylboronic acid CAS 5720-07-0, I recommend treating it as a specification-controlled Suzuki coupling intermediate rather than purchasing only by name and CAS number. The key checks are chemical identity, assay, water content, residual solvents, packaging, batch documentation, and the supplier’s ability to provide repeatable lots. At Maison Chemical, I support buyers by aligning the requested grade, quantity, documentation, and delivery plan before quotation.

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4-Methoxyphenylboronic acid is also known as 4-anisylboronic acid or (4-methoxyphenyl)boronic acid. Its commonly listed molecular formula is C7H9BO3, and its molecular weight is approximately 151.96 g/mol. The material is an aryl boronic acid used primarily as a boron-containing building block in organic synthesis, especially for carbon–carbon bond formation with suitable halides or related coupling partners.

Who This Guide Is For

This guide is intended for procurement teams, process chemists, medicinal chemistry groups, custom synthesis companies, and manufacturers evaluating 4-Methoxyphenylboronic acid for laboratory or production use. It is also useful when several suppliers quote the same CAS number but provide different specifications, pack sizes, or documentation. My goal is to help you compare offers on technical suitability and supply reliability, not just unit price.

The correct purchasing decision depends on the intended reaction, scale, downstream purification strategy, and internal quality requirements. A research laboratory may need a practical small pack with a standard certificate of analysis, while a process-development or commercial project may require lot consistency, controlled packaging, and pre-shipment documentation. These needs should be stated before a supplier prepares a final quotation.

Basic Chemical Context

4-Methoxyphenylboronic acid contains an aryl group bearing a methoxy substituent and a boronic acid functional group. In synthetic chemistry, the boronic acid group can participate in palladium-catalyzed cross-coupling reactions, including Suzuki-type transformations, when the reaction conditions and partner substrates are appropriate. Actual conversion depends on the catalyst system, base, solvent, temperature, substrate structure, and process controls.

The compound is generally handled as a solid intermediate, but its physical condition can vary with storage history, moisture exposure, and packaging. I therefore advise buyers not to define acceptance only by appearance. Identity and quality should be confirmed using the analytical methods appropriate to the application, such as NMR, chromatography, mass spectrometry, or other methods specified in the buyer’s internal procedure.

Specification Overview for Buyer Evaluation

A sourcing specification should separate fixed identity information from batch-release requirements. The CAS number and molecular formula help establish what material is being discussed, but they do not by themselves define acceptable assay, impurities, or physical condition. Before ordering, I suggest asking the supplier to confirm the exact product name, CAS 5720-07-0, molecular weight of approximately 151.96 g/mol, grade, and intended use.

Evaluation Item What to Confirm Why It Matters
Identity Product name, CAS number, formula, and analytical identity Reduces the risk of receiving a positional isomer or incorrectly labeled material
Assay and purity Specification, test method, and reported batch result Helps estimate usable reagent content and reaction consistency
Moisture and physical condition Water-related requirements, appearance, and storage guidance Boronic acids may require controlled handling depending on the process
Impurity profile Known process impurities, residual solvents, and chromatographic data where applicable Supports process development and downstream purification planning
Documentation COA, SDS, packing information, and traceability details Supports internal approval, transport review, and quality records

For a new supplier, I recommend requesting a representative COA before final approval and checking whether the listed methods match your organization’s requirements. If your process is sensitive to water, palladium poisons, or specific organic impurities, those parameters should be discussed explicitly rather than assumed to be covered by a general purity value. Any numerical acceptance limit should be agreed in writing and confirmed against the actual batch documentation.

Matching the Material to the Application

Research and Medicinal Chemistry

For discovery chemistry, the primary requirements are usually correct identity, suitable purity, practical pack sizes, and rapid access to documentation. Small quantities may be appropriate for parallel synthesis or route screening, but the selected supplier should still provide enough information for scientists to reproduce experiments. I suggest recording the supplier lot number in the laboratory notebook because lot traceability becomes important when reaction performance differs between experiments.

Process Development and Scale-Up

At larger scale, procurement should evaluate more than the quoted price per kilogram. The buyer should review batch-to-batch consistency, impurity control, packaging configuration, storage conditions, and the supplier’s ability to reserve or reproduce material. A sample approval process can reduce risk before a larger purchase, especially when the intermediate is entering a validated or tightly controlled synthetic route.

Custom Synthesis and Manufacturing

For contract or commercial work, the supplier must understand the customer’s quality agreement, release procedure, and delivery schedule. The same CAS number may be acceptable for one project and insufficient for another if the customer requires particular residual solvent limits, elemental impurity information, or change-control support. I recommend sharing the relevant specification early so the quotation reflects the real compliance and service requirements.

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A Practical Supplier Selection Framework

I use a step-by-step review to help buyers compare 4-Methoxyphenylboronic acid suppliers consistently. First, I confirm the chemical identity and intended application. Second, I compare the required specification with the supplier’s standard product specification, identifying any parameters that require custom testing or additional documentation.

  1. Define the demand: state the required quantity, pack size, delivery destination, target date, and forecast if repeat purchasing is expected.
  2. Confirm technical fit: review identity, assay, impurity profile, moisture expectations, appearance, and analytical methods.
  3. Review documentation: request the COA, SDS, product specification, packing details, and available traceability information.
  4. Assess logistics: confirm lead time, shipment conditions, export documents, and whether the material is available from stock or requires production.
  5. Approve the lot: compare the sample or pre-shipment documentation with your internal acceptance criteria before placing a larger order.

Three commercial data points should always be requested in writing: the quoted price per requested unit, the minimum order quantity in kilograms or grams, and the estimated lead time in days or weeks. These figures are not universal product facts and can change with quantity, destination, packaging, production scheduling, and documentation requirements. A quotation that excludes one of these items may not provide a meaningful basis for comparison.

Pricing, MOQ, and Lead-Time Considerations

Pricing for 4-Methoxyphenylboronic acid is influenced by quantity, purity target, packaging, testing, and whether the product is supplied from available inventory or manufactured against order. Small research packs often have a higher unit cost because packaging and handling represent a larger share of the transaction. Larger orders may improve the unit economics, but buyers should balance this against shelf-life, storage capacity, and project certainty.

Minimum order quantities should be evaluated alongside consumption forecasts. If annual demand is uncertain, a staged purchasing plan may reduce inventory exposure, while a firm forecast can help a supplier plan production and offer more stable delivery. I encourage buyers to ask whether partial shipment, reserved inventory, or repeat-order planning is available when the project has multiple milestones.

Common Sourcing Mistakes

One common mistake is selecting a supplier solely on the lowest quoted price without checking what is included in the specification. Another is assuming that a standard COA automatically covers every parameter required by a customer or regulatory procedure. Buyers should also avoid postponing logistics questions until after technical approval, because export paperwork, packaging, or production timing can affect the final delivery schedule.

A further risk is treating “high purity” as a complete technical description. Purity may be determined by different analytical methods, and two suppliers may report results that are not directly comparable. I recommend asking for the method, the actual batch result, and any known limitations before approving the material for a sensitive synthetic route.

How Maison Chemical Supports Procurement

At Maison Chemical, I approach this product as a B2B sourcing project with both technical and commercial dimensions. I can help buyers clarify the required grade, pack size, target quantity, documentation package, and delivery destination before a quotation is finalized. Where a customer has a defined specification, the request can be reviewed against the available product information rather than relying on a generic catalog description.

For repeat purchasing, I recommend establishing a clear purchasing record that includes the approved specification, packaging format, lot documentation, and communication process for future orders. This creates a more practical basis for continuity than relying on product name alone. Availability, MOQ, lead time, and test documentation should be confirmed for each specific order because they may vary by project and shipment schedule.

Key Takeaways

  • 4-Methoxyphenylboronic acid CAS 5720-07-0 is an aryl boronic acid building block used mainly in organic synthesis and cross-coupling research.
  • Its commonly listed formula is C7H9BO3, with an approximate molecular weight of 151.96 g/mol.
  • Identity, assay, impurity profile, moisture-related requirements, packaging, and documentation should be reviewed together.
  • Price, MOQ, and lead time must be confirmed for the specific quantity, destination, grade, and delivery plan.
  • A representative COA and agreed acceptance criteria can reduce technical and purchasing risk before scale-up.

Conclusion and Next Steps

The best way to source 4-Methoxyphenylboronic acid CAS 5720-07-0 is to match the material specification to the intended synthesis and then evaluate suppliers on documentation, consistency, logistics, and service—not price alone. I recommend preparing a short inquiry that includes your required quantity, purity or assay target, pack size, destination, delivery date, and documentation needs. This allows Maison Chemical to review the request accurately and provide a more useful B2B quotation.

To begin, send Maison Chemical your target quantity, application stage, preferred specification, and any customer or internal quality requirements. I can then help identify the appropriate supply route, confirm available documentation, and clarify MOQ and lead-time expectations for your project.

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